Torsades de Pointes in Takotsubo Cardiomyopathy with QT Prolongation
نویسنده
چکیده
Takotsubo cardiomyopathy, or stress-induced cardiomyopathy, is characterized by reversible left ventricular apical ballooning associated with emotional or physiologic stress, mimicking acute myocardial infarction in the absence of significant coronary artery disease at angiography. Although the prognosis for patients with Takotsubo cardiomyopathy is relatively good, it is reported to be associated with long QT syndrome and torsades de pointes (TdP) which is a fatal polymorphic ventricular tachyarrhythmia. However, only QT prolongation abnormalities is not enough to induce TdP, and other factors associated with Takotsubo cardiomyopathy seem to be needed for the induction of TdP. In this chapter, the mechanism of TdP in Takotsubo cardiomyopathy with QT prolongation is discussed.
منابع مشابه
Long QT Syndrome and Torsade de Pointes Associated with Takotsubo Cardiomyopathy
Prolongation of QTc interval associated with Takotsubo cardiomyopathy (TC) has previously been reported in published case series. We report an unusual case of a patient who presented with TC associated with long-QT syndrome and developed cardiac arrest secondary to torsade de pointes. Since QT prolongation and bradycardia persisted after the resolution of TC, the patient received permanent pace...
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Takotsubo cardiomyopathy, also known as stress-induced cardiomyopathy, is a disease in which the patient exhibits transient, reversible left ventricular dysfunction that is triggered by physical or emotional stress. Prolongation of QT interval, a risk factor for arrhythmia and sudden death, has been reported to be prevalent among patients with Takotsubo cardiomyopathy and is also observed in th...
متن کاملTakotsubo cardiomyopathy and QT interval prolongation: who are the patients at risk for torsades de pointes?
OBJECTIVES QT interval prolongation is prevalent among patients with Takotsubo cardiomyopathy (TC), whereas torsades de pointes (TdP) has rarely been reported in these patients. We studied all peer-reviewed reports on TC-associated QT interval prolongation and all peer-reviewed reports on TC-associated TdP to characterize the clinical circumstances leading to TdP in patients with TC. METHODS ...
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A 71-year-old woman collapsed while working as a grocery store cashier. CPR was performed and an AED revealed torsades de pointes (TdP). She was subsequently defibrillated resulting in restoration of sinus rhythm with a QTc interval of 544 msec. Further evaluation revealed a diagnosis of Takotsubo Cardiomyopathy (TCM) contributing to the development of a multifactorial acquired long QT syndrome...
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